2019 Journal
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2019
Date |
Presenter |
Title |
Journal |
01 / 04 |
YU Lee |
Epigenetic silencing of ZNF132 mediated by methylation-sensitive Sp1 binding promotes cancer progression in esophageal squamous cell carcinoma |
Cell Death Dis. |
01 / 11 |
MJ Cho |
A conserved enhancer regulates Il9 expression in multiple lineages |
Nat. Commun. |
01 / 18 |
JW Lee |
Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress |
Nat. Commun. |
01 / 25 |
DW Kim |
Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming |
Nat. Commun. |
02 / 08 |
EJ Choi |
A map of constrained coding regions in the human genome | Nature Genet. |
02 / 15 |
Khanh Chu |
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas | Nat. Commun. |
03 / 04 |
JH Hwang |
Sense-antisense lncRNA pair encoded by locus 6p22.3 determines neuroblastoma susceptibility via the USP36-CHD7-SOX9 regulatory axis |
Cancer Cell |
03 / 28 |
JY Lee |
Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements |
Nature Genet. |
04 / 19 | HR Shim | Identification of differentially methylated cell types in epigenome-wide association studies | Nat. Methods |
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference | Nat. Commun. | ||
04 / 26 | HR Shim | Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen | Nat. Commun. |
05 / 03 | HR Shim | KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer | Cancer Cell |
05 / 10 | HR Shim | Somatic mutations increase hepatic clonal fitness and regeneration in chronic liver disease | Cell |
05 / 17 | SC Kim | Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies | Cancer Cell |
05 / 24 | SC Kim | Whole genome sequencing put forward hypotheses on metastasis evolution and therapy in colorectal cancer | Nat. Commun. |
06 / 21 | JM Kim | A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in in primary models refractory to or ineligible for HER2-targeted therapy | Cancer Cell |
06 / 28 | JI Jun | Defining UHRF1 domains that support maintenance of human colon cancer DNA methylation and oncogenic properties | Cancer Cell |
07 / 05 | YT Kim | Quantitative evidence for early metastatic seeding in colorectal cancer | Nature Genet. |
07 / 12 | JY Lee | PI3Ka-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease | Nat. Commun. |
07 / 19 | MJ Cho | Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions | Immunity |
07 / 26 | YU Lee | Antisense lncRNA transcription mediates DNA demethylation to drive stochastic protocadherin a promoter choice | Cell |
08 / 02 | JH Hwang | Developmental dynamics of lncRNAs across mammalian organs and species | Nature |
08 / 16 | JY Lee | Characterizing the major structural variant alleles of the human genome | Cell |
08 / 30 | MH Jung | Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits | Nat. Commun. |
09 / 20 | HR Shim | Accurate detection of m6A RNA modifications in native RNA sequences | Nat. Commun. |
09 / 27 | YT Kim | Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells | Nature Genet. |
10 / 18 | HJ Kim | Synaptic proximity enables NMDAR signaling to promote brain metastasis | Nature |
10 / 25 | JM Kim | Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophage | Proc. Natl. Acad. Sci. |
11 / 01 | JM Kim | Cell survival and cytokine release after inflammasome activation is regulated by the Toll-IL- 1R protein SARM | Immunity |
11 / 08 | JI Jun | Whole-genome sequencing reveals novel tendem-duplication hotspots and a prognostic mutational signature in gastric cancer | Nat. Commun. |
11 / 15 | SC Kim | Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients | Nat. Commun. |
11 / 22 | JY Lee | Protein Kinase D at the Golgi controls NLRP3 inflammasome activation | J. Exp. Med. |
11 / 29 | YU Lee | Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers | Nat. Commun. |
12 / 05 | MJ Cho | Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis | Nature |
12 / 13 | EJ Choi | Functional enhancers shape extrachromosomal oncogene amplifications | Cell |
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